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1.
J Pers Med ; 14(3)2024 Mar 13.
Artigo em Inglês | MEDLINE | ID: mdl-38541047

RESUMO

In recent years, although life expectancy has increased significantly, non-communicable diseases (NCDs) continue to pose a significant threat to the health of the global population. Therefore, eating habits have been recognized as key modifiable factors that influence people's health and well-being. For this reason, it is interesting to study dietary patterns, since the human diet is a complex mixture of macronutrients, micronutrients, and bioactive compounds, and can modulate multiple physiological processes, including immune function, the metabolism, and inflammation. To ensure that the data we acquired were current and relevant, we searched primary and secondary sources, including scientific journals, bibliographic indexes, and databases in the last 15 years with the most relevant articles. After this search, we observed that all the recent research on NCDs suggests that diet is a critical factor in shaping an individual's health outcomes. Thus, cardiovascular, metabolic, mental, dental, and visual health depends largely on the intake, habits and patterns, and nutritional behaviors. A diet high in processed and refined foods, added sugars, and saturated fats can increase the risk of developing chronic diseases. On the other hand, a diet rich in whole, nutrient-dense foods, such as vegetables, fruits, nuts, legumes, and a high adherence to Mediterranean diet can improve health's people.

2.
J Funct Morphol Kinesiol ; 9(2)2024 Mar 22.
Artigo em Inglês | MEDLINE | ID: mdl-38525758

RESUMO

An increase in the delivery and use of oxygen to the musculature in physically active subjects are determinants of improving health-related aerobic capacity. Additional health benefits, such as an increase in the muscle mass and a decrease in fat mass, principally in the legs, could be achieved with weekly global physical activity levels of more than 300 min. The objective was to compare the muscle vascular and metabolic profiles of physically very active and inactive subjects. Twenty healthy men participated in the study; ten were assigned to the physically very active group (25.5 ± 4.2 years; 72.7 ± 8.1 kg; 173.7 ± 7.6 cm) and ten to the physically inactive group (30.0 ± 7.4 years; 74.9 ± 11.8 kg; 173.0 ± 6.4 cm). The level of physical activity was determined by the Global Physical Activity Questionnaire (GPAQ). A resting vascular occlusion test (5 min of an ischemic phase and 3 min of a reperfusion phase) was used, whereas a near-field infrared spectroscopy (NIRS) device was used to evaluate the muscle oxygenation in the right vastus lateralis of the quadriceps muscle. The area under the curve of the deoxyhemoglobin (HHb) during the ischemic phase and above the curve of the tissue saturation index (TSI) during the reperfusion phase were obtained to determine muscle metabolic and vascular responses, respectively. Physically very active group showed a higher absolute HHb (3331.9 ± 995.7 vs. 6182.7 ± 1632.5 mmol/s) and lower TSI (7615.0 ± 1111.9 vs. 5420.0 ± 781.4 %/s) and relative to body weight (46.3 ± 14.6 vs. 84.4 ± 27.1 mmol/s/kg and 106.0 ± 20.6 vs. 73.6 ± 13.8 %/s/kg, respectively), muscle mass (369.9 ± 122.2 vs. 707.5 ± 225.8 mmol/kg and 829.7 ± 163.4 vs. 611.9 ± 154.2 %/s/kg) and fat mass (1760.8 ± 522.9 vs. 2981.0 ± 1239.9 mmol/s/kg and 4160.0 ± 1257.3 vs. ±2638.4 ± 994.3 %/s/kg, respectively) than physically inactive subjects. A negative correlation was observed between HHb levels and TSI (r = -0.6; p < 0.05). Physically very active men (>300 min/week) present better muscle oxidative metabolism and perfusion and perform significantly more physical activity than physically inactive subjects. Extra benefits for vascular health and muscle oxidative metabolism are achieved when a subject becomes physically very active, as recommended by the World Health Organization. In addition, a higher level of physical activity determined by GPAQ is related to better vascular function and oxidative metabolism of the main locomotor musculature, i.e., the quadriceps.

3.
Children (Basel) ; 11(3)2024 Mar 12.
Artigo em Inglês | MEDLINE | ID: mdl-38539372

RESUMO

Modified invasion games promote the development of real and perceived motor competence. Children with higher motor competence are more likely to participate in physical activity practice and to remain in it, both in adolescence and adulthood. (1) Background: The purpose of this study is to determine the effect of modified invasion games on the real motor competence and self-assessment of the physical condition fifth-grade students from a private school in Viña del Mar, Chile. (2) Methods: 40 girls and boys with an average age of 11.47 years (SD = 0.554) participated in this study during a 12-week intervention. The MOBAK 5-6 battery was used to assess actual motor competence, the SEMOK questionnaire was used to determine perceived motor competence, the International Fitness Scale (IFIS) self-assessment questionnaire was used to assess perceived physical fitness, and the weight/size ratio was used to determine BMI. A Friedman's nonparametric ANOVA analysis was applied to determine the effect of the intervention, in addition to an analysis of covariance (ANCOVA) to identify the influence of the covariates on motor competence. (3) Results: No statistically significant differences were established between weight, BMI, and waist circumference. There was a statistically significant difference after the intervention in the actual motor competence of object control (p = 0.005) and perceived motor competence of object control (p ≤ 0.001) (4) Conclusions: An intervention based on modified invasion games is effective for the improvement of actual and perceived motor competence of object control. It was not possible to identify a positive effect on the self-assessment of muscle strength after the intervention.

4.
Int. j. morphol ; 41(6): 1648-1652, dic. 2023. tab
Artigo em Espanhol | LILACS | ID: biblio-1528790

RESUMO

El proceso madurativo tiene una gran influencia sobre los factores antropométricos y las capacidades físicas del atleta, y por tanto, sobre el proceso de selección de talentos deportivos. El objetivo de este trabajo fue analizar el estado madurativo y las características antropométricas junto con la comparación de estos datos por sexo en una muestra de 39 jugadores jóvenes de voleibol dentro de un proceso de selección de talentos (19 damas de 14,88±1,05 años y 13 varones de 15,1 años). Se obtuvieron datos de edad cronológica, altura, peso, altura sentado, altura de la madre y padre, la edad pico de crecimiento, el "timing" o periodo de tiempo por encima o por debajo de la edad pico, altura al final del proceso madurativo, el porcentaje actual de altura máxima, los centímetros restantes y el estado madurativo (pre-púber, púber o pos-púber). Los jugadores mostraron una mayor altura en el momento de las mediciones (179,92±6,87 vs 171,05±4,80; p<0,001), así como una mayor altura final calculada (189,46±3,73 vs 178,52±5,17; p<0,001), en comparación a las jugadoras. El pico en la velocidad de crecimiento también fue superior en los jugadores (14,56±0,44 vs 12,60±0,57; p<0,001), aunque su timing era inferior al de las jugadoras (0,531±1,19 vs 2,27±0,64; p<0,001). Esto se debió a un mayor porcentaje de jugadores masculinos en estados puberales, incluyendo un jugador en estadio pre-puberal, mientras que fue abundante la presencia de jugadoras en estado pospuberal. Estos datos reflejan la gran cantidad de jugadores que tienden a estar en periodos avanzados de maduración en procesos de selección de talentos. Por tanto, entrenadores y seleccionadores deben contemplar estas variables para evitar sesgos en el proceso de identificación del talento deportivo.


SUMMARY: The maturation process has a great influence on the anthropometric factors and physical capabilities of the athlete, and therefore, on the selection process of sporting talents. The objective of this work was to analyze the maturational state and anthropometric characteristics together with the comparison of these data by sex in a sample of 39 young volleyball players within a talent selection process (19 ladies of 14.88±1. 05 years old and 13 males aged 15.1 years). Data were obtained on chronological age, height, weight, sitting height, height of the mother and father, peak age of growth, timing or period of time above or below the peak age, height at the end of the process. maturation, the current percentage of maximum height, the remaining centimeters and the maturation status (pre-pubertal, pubertal or post-pubertal). The players showed a greater height at the time of the measurements (179.92±6.87 vs. 171.05±4.80; p<0.001), as well as a greater final calculated height (189.46±3.73 vs. 178.52±5.17; p<0.001), compared to the female players. The peak in growth speed was also higher in male players (14.56±0.44 vs 12.60±0.57; p<0.001), although their timing was lower than that of female players (0.531±1.19 vs 2.27±0.64; p<0.001). This was due to a higher percentage of male players in pubertal states, including one player in a pre-pubertal stage, while the presence of female players in a post-pubertal stage was abundant. These data reflect the large number of players who tend to be in advanced periods of maturation in talent selection processes. Therefore, coaches and selectors must consider these variables to avoid biases in the process of identifying sporting talent.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Antropometria , Aptidão Física , Voleibol , Fatores Sexuais , Estudos Transversais
5.
J Funct Morphol Kinesiol ; 8(4)2023 Oct 26.
Artigo em Inglês | MEDLINE | ID: mdl-37987485

RESUMO

This study aimed to associate body composition with fractional oxygen extraction at rest in healthy adult men. Fourteen healthy adults (26.93 ± 2.49 years) from Chile participated. Body composition was assessed with octopole bioimpedance, and resting muscle oxygenation was evaluated in the vastus lateralis quadriceps with near-infrared spectroscopy (NIRS) during a vascular occlusion test, analyzing the muscleVO2, resaturation velocity during reactive hyperemia via the muscle saturation index (%TSI), and the area above the curve of HHb (AACrep). It was observed that the total and segmented fat mass are associated with lower reoxygenation velocities during hyperemia (p = 0.008; ß = 0.678: p = 0.002; ß = 0.751), and that the total and segmented skeletal muscle mass are associated with higher reoxygenation velocities during hyperemia (p = 0.020; ß = -0.614: p = 0.027; ß = -0.587). It was also observed that the total and segmented fat mass were associated with a higher area above the curve of HHb (AACrep) during hyperemia (p = 0.007; ß = 0.692: p = 0.037; ß = 0.564), and that total and segmented skeletal muscle mass was associated with a lower area above the curve of HHb (AACrep) during hyperemia (p = 0.007; ß = -0.703: p = 0.017; ß = -0.632). We concluded that fat mass is associated with lower resaturation rates and lower resting fractional O2 extraction levels. In contrast, skeletal muscle mass is associated with higher resaturation rates and fractional O2 extraction during reactive hyperemia. The AACrep may be relevant in the evaluation of vascular adaptations to exercise and metabolic health.

6.
Front Public Health ; 11: 1172391, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37920579

RESUMO

Asthma is one of the most common atopic disorders in all stages of life. Its etiology is likely due to a complex interaction between genetic, environmental, and lifestyle factors. Due to this, different non-pharmacological interventions can be implemented to reduce or alleviate the symptoms caused by this disease. Thus, the present narrative review aimed to analyze the preventive and non-pharmacological interventions such as physical exercise, physiotherapy, nutritional, ergonutritional, and psychological strategies in asthma treatment. To reach these aims, an extensive narrative review was conducted. The databases used were MedLine (PubMed), Cochrane (Wiley), Embase, PsychINFO, and CinAhl. Asthma is an immune-mediated inflammatory condition characterized by increased responsiveness to bronchoconstrictor stimuli. Different factors have been shown to play an important role in the pathogenesis of asthma, however, the treatments used to reduce its incidence are more controversial. Physical activity is focused on the benefits that aerobic training can provide, while physiotherapy interventions recommend breathing exercises to improve the quality of life of patients. Nutritional interventions are targeted on implement diets that prioritize the consumption of fruits and vegetables and supplementation with antioxidants. Psychological interventions have been proposed as an essential non-pharmacological tool to reduce the emotional problems associated with asthma.


Assuntos
Asma , Qualidade de Vida , Humanos , Asma/prevenção & controle , Exercício Físico , Terapia por Exercício
7.
Cells ; 12(20)2023 10 15.
Artigo em Inglês | MEDLINE | ID: mdl-37887299

RESUMO

Epithelial transport is a multifaceted process crucial for maintaining normal physiological functions in the human body. This comprehensive review delves into the pathophysiological mechanisms underlying epithelial transport and its significance in disease pathogenesis. Beginning with an introduction to epithelial transport, it covers various forms, including ion, water, and nutrient transfer, followed by an exploration of the processes governing ion transport and hormonal regulation. The review then addresses genetic disorders, like cystic fibrosis and Bartter syndrome, that affect epithelial transport. Furthermore, it investigates the involvement of epithelial transport in the pathophysiology of conditions such as diarrhea, hypertension, and edema. Finally, the review analyzes the impact of renal disease on epithelial transport and highlights the potential for future research to uncover novel therapeutic interventions for conditions like cystic fibrosis, hypertension, and renal failure.


Assuntos
Fibrose Cística , Hipertensão , Humanos , Fibrose Cística/genética , Regulador de Condutância Transmembrana em Fibrose Cística/metabolismo , Células Epiteliais/metabolismo , Transporte de Íons/fisiologia
8.
Int. j. morphol ; 41(5): 1411-1420, oct. 2023. ilus, tab
Artigo em Inglês | LILACS | ID: biblio-1521016

RESUMO

SUMMARY: This study aims to assess the nutritional status of Aymara and non-Aymara children in Arica, comparing anthropometric measurements of boys and girls aged 4-10 to inform interventions for child health and development. We conducted a non-experimental, quantitative, cross-sectional study in Arica, Chile. The sample included 458 children, with equal representation of Aymara and non-Aymara children from diverse socioeconomic backgrounds. Trained research assistants collected anthropometric data using standardized techniques. IBM SPSS statistical software was used for data analysis, including Student's t-test and the Levene test. Both Aymara and non-Aymara children showed high prevalence of overweight and obesity. Boys had a meso-endomorph somatotype, while girls had an endomorph somatotype. Among 8-year-olds, non-Aymara children had a slightly higher mean body weight (35.87, SD 4.50) compared to Aymara children (32.27, SD 4.31), but the difference was not statistically significant (p>0.05). However, 10-year-old Aymara girls had a significantly higher mean body mass index (22.34, SD 4.21) than non-Aymara girls (20.10, SD 3.58) (p=0.05). Regarding body fat percentage, 10-year- old non-Aymara girls had a slightly higher mean (31.01, SD 5.64) than Aymara girls (26.12, SD 5.63), but the difference was not statistically significant (p>0.05). The study found high levels of overweight and obesity in children from northern Chile, increasing with age for both Aymara and non-Aymara groups. The somatotype patterns were consistent across both groups. Although the differences between Aymara and non-Aymara children were not statistically significant, the Aymara group showed slightly higher levels of overweight and obesity. Further research with a larger sample size is needed to confirm these results and identify potential trends. Efforts should focus on promoting healthy nutrition and physical activity to address the growing problem of overweight and obesity in this region.


Este estudio tiene como objetivo evaluar el estado nutricional de los niños Aymaras y no Aymaras en Arica, comparando las medidas antropométricas de niños y niñas de 4 a 10 años para informar las intervenciones para la salud y el desarrollo infantil. Realizamos un estudio no experimental, cuantitativo, de corte transversal en Arica, Chile. La muestra incluyó a 458 niños, con igual representación de niños Aymaras y no Aymaras de diversos estratos socioeconómicos. Asistentes de investigación capacitados recolectaron datos antropométricos utilizando técnicas estandarizadas. Se utilizó el software estadístico IBM SPSS para el análisis de datos, incluyendo la prueba t de Student y la prueba de Levene. Tanto los niños Aymaras como los no Aymaras presentaron una alta prevalencia de sobrepeso y obesidad. Los niños tenían un somatotipo meso-endomorfo, mientras que las niñas tenían un somatotipo endomorfo. Entre los niños de 8 años, los niños no Aymaras tenían un peso corporal medio ligeramente superior (35,87, DE 4,50) en comparación con los niños Aymaras (32,27, DE 4,31), pero la diferencia no fue estadísticamente significativa (p>0,05). Sin embargo, las niñas Aymaras de 10 años tenían un índice de masa corporal medio significativamente mayor (22,34, SD 4,21) que las niñas no Aymaras (20,10, SD 3,58) (p=0,05). En cuanto al porcentaje de grasa corporal, las niñas no Aymaras de 10 años tuvieron una media ligeramente superior (31,01, DE 5,64) que las niñas Aymaras (26,12, DE 5,63), pero la diferencia no fue estadísticamente significativa (p>0,05). El estudio encontró altos niveles de sobrepeso y obesidad en niños del norte de Chile, aumentando con la edad tanto para los grupos Aymaras como para los no Aymaras. Los patrones de somatotipo fueron consistentes en ambos grupos. Aunque las diferencias entre los niños Aymaras y no Aymaras no fueron estadísticamente significativas, el grupo Aymara mostró niveles ligeramente más altos de sobrepeso y obesidad. Se necesita más investigación con un tamaño de muestra más grande para confirmar estos resultados e identificar tendencias potenciales. Los esfuerzos deben centrarse en promover una nutrición saludable y la actividad física para abordar el creciente problema del sobrepeso y la obesidad en esta región.


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Composição Corporal , Índios Sul-Americanos , Antropometria , Somatotipos , Estatura , Peso Corporal , Índice de Massa Corporal , Chile , Tecido Adiposo , Estado Nutricional , Estudos Transversais , Sobrepeso , Obesidade
9.
Int. j. morphol ; 41(5): 1323-1329, oct. 2023. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-1521020

RESUMO

La composición corporal engloba una serie de variables relacionadas con la salud e influye en la condición física. A pesar de ello, existe poca evidencia sobre sus efectos en la capacidad operativa en militares. El objetivo de este estudio fue relacionar la composición corporal, la condición física y la capacidad operativa de militares chilenos. Participaron 57 militares chilenos (26,9 ± 4,8 años), con especialización operativa en infantería. La composición corporal fue evaluada con bioimpedancia octopolar estimando masa libre de grasa, tejido muscular y tejido adiposo, entre otras variables. También se realizaron las siguientes pruebas de condición física: 5000 m planos, dominadas, abdominales y flexibilidad, así como cuatro pruebas específicas de actividades operativas militares específicas (situación de combate simulado). Los resultados mostraron un porcentaje de tejido muscular de 45,4 ± 2,9 % (IC95%: 44,6 - 46,2), mientras que el porcentaje de tejido adiposo fue de 20,3 ± 4,9 % (IC95%: 14,7 - 17,3). Se encontraron correlaciones negativas de pequeña magnitud entre el tiempo de carrera (5000 m) y el tejido muscular (%) (r = -0,275) y positiva con el tejido adiposo (%) (r = 0,294). Sin embargo, se observaron correlaciones de alta magnitud entre dominadas y tejido muscular (%) (r = 0,517) y tejido adiposo (%) (r = -0,558). El tejido adiposo se relacionó negativamente con la capacidad aeróbica, fuerza de brazos(??) y fuerza resistencia abdominal, mientras que el tejido muscular se relacionó positivamente con estas mismas variables. No se apreciaron correlaciones entre la composición corporal y la capacidad operativa militar (p<0,05). Se concluye que la composición corporal y la condición física no se relacionan con la capacidad operativa militar en situación de combate en especialistas en infantería, pero si la composición corporal se relaciona con la fuerza y la capacidad cardiorrespiratoria.


SUMMARY: Body composition encompasses a series of variables that are health-related and influence physical condition. Nevertheless, there is little evidence on its effects on the operational capacity of the military. The objective of this study was to relate the body composition, the physical condition and the operational capacity of the Chilean military. Fifty-seven Chilean soldiers (26.9 ± 4.8 years) participated, with operational specialization in infantry. Body composition was evaluated with octopolar bioimpedance, estimating fat- free mass, muscle tissue, and adipose tissue, among other variables. The following physical condition tests were also carried out: 5000 m flat, pull-ups, abdominals and flexibility, as well as four specific tests of specific military operational activities (simulated combat situation). The results showed a percentage of muscle tissue of 45.4 ± 2.9 % (95%CI: 44.6 - 46.2), while the percentage of adipose tissue was 20.3 ± 4.9 % (95%CI). : 14.7-17.3). Negative correlations of small magnitude were found between race time (5000 m) and muscle tissue (%) (r = -0.275) and positive with adipose tissue (%) (r = 0.294). However, high magnitude correlations were observed between pull-ups and muscle tissue (%) (r = 0.517) and adipose tissue (%) (r = -0.558). Adipose tissue was negatively related to aerobic capacity, arm strength, and abdominal endurance strength, while muscle tissue was positively related to these same variables. No correlations were found between body composition and military operational capacity (p<0.05). It is concluded that body composition and physical condition are not related to military operational capacity in combat situations in infantry specialists, but body composition is related to strength and cardiorespiratory capacity.


Assuntos
Humanos , Masculino , Adulto , Adulto Jovem , Composição Corporal , Exercício Físico , Desempenho Físico Funcional , Militares , Chile , Antropometria , Tecido Adiposo , Impedância Elétrica
10.
Biomedicines ; 11(9)2023 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-37760929

RESUMO

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated in the pathogenesis of various brain diseases, including neurodegenerative disorders, stroke, and psychiatric illnesses. This review paper provides a comprehensive overview of the intricate relationship between mitochondria and brain disease, focusing on the underlying pathological mechanisms and exploring potential therapeutic opportunities. The review covers key topics such as mitochondrial DNA mutations, impaired oxidative phosphorylation, mitochondrial dynamics, calcium dysregulation, and reactive oxygen species generation in the context of brain disease. Additionally, it discusses emerging strategies targeting mitochondrial dysfunction, including mitochondrial protective agents, metabolic modulators, and gene therapy approaches. By critically analysing the existing literature and recent advancements, this review aims to enhance our understanding of the multifaceted role of mitochondria in brain disease and shed light on novel therapeutic interventions.

11.
Int. j. morphol ; 41(4): 1123-1127, ago. 2023. ilus, tab
Artigo em Inglês | LILACS | ID: biblio-1514337

RESUMO

SUMMARY: Anthropometric characteristics, including body size, shape, and composition, can have a significant impact on sports performance due to their influence on various physiological and biomechanical factors. However, limited research has been conducted on the anthropometric characteristics of highly trained throwing para-athletes. The purpose of this study was to describe the anthropometric characteristics, handgrip strength, and upper limb bilateral asymmetries of highly trained Chilean shot put para-throwers. Five male Chilean shot put para-athletes (average age of 38.8 ± 7.7 years) were assessed for their anthropometric characteristics, including skinfold thickness at six anatomical sites, girth at five sites, and bone breadth at two sites. Handgrip strength and bilateral asymmetries were also measured. The body mass and height of the athletes were found to be 90.5 ± 5.1 kg and 179.1 ± 8.9 cm, respectively. The athletes were found to have an endo-mesomorph somatotype (4.4-6.9-1.0) with high levels of fat mass (25.7 ± 2.8 %) and skeletal muscle mass (39.1 ± 3.7 %). The handgrip strength of the athletes was found to be 66.4 ± 6.7 kg with a bilateral asymmetry of 6.5 ± 6.2 %, with the dominant hand showing greater strength. The results indicate that the shot put para-athletes have a somatotype characterized by increased muscularity and body fat, along with a considerable stature. Although handgrip strength was found to be high, the athletes showed bilateral asymmetry, which requires further investigation to determine the cause and implications.


Las características antropométricas, incluido el tamaño, forma y composición del cuerpo, pueden tener un impacto significativo en el rendimiento deportivo debido a su influencia en diversos factores fisiológicos y biomecánicos. Sin embargo, las investigaciones sobre las características antropométricas para-atletas de lanzamiento altamente entrenados son limitadas. El propósito de este estudio fue describir las características antropométricas, la fuerza de prensión manual y las asimetrías bilaterales de miembros superiores de paralanzadores chilenos altamente entrenados en lanzamiento de la bala. Se evaluaron las características antropométricas de cinco atletas masculinos chilenos de lanzamiento de bala (edad promedio de 38,8 ± 7,7 años), incluido el grosor de los pliegues cutáneos en seis sitios anatómicos, la circunferencia en cinco sitios y la anchura de los huesos en dos sitios. También se midieron la fuerza de prensión manual y las asimetrías bilaterales. Se encontró que la masa corporal y la altura de los atletas eran 90,5 ± 5,1 kg y 179,1 ± 8,9 cm, respectivamente. Los atletas tenían un somatotipo endo-mesomorfo (4.4-6.9-1.0) con altos niveles de masa grasa (25.7 ± 2.8 %) y masa muscular esquelética (39.1 ± 3.7 %). Se encontró además que la fuerza de prensión manual de los atletas era de 66,4 ± 6,7 kg con una asimetría bilateral de 6,5 ± 6,2 %, mostrando mayor fuerza la mano dominante. Los resultados indican que los atletas de lanzamiento de bala tienen un somatotipo caracterizado por una mayor musculatura y grasa corporal, junto con una estatura considerable. Aunque se encontró que la fuerza de agarre era alta, los atletas mostraron asimetría bilateral, lo que requiere de más investigaciones para determinar las causa e implicaciones.


Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Antropometria , Força da Mão , Deformidades Congênitas das Extremidades Superiores , Paratletas , Somatotipos , Composição Corporal , Chile , Esportes para Pessoas com Deficiência
12.
Int J Mol Sci ; 24(13)2023 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-37445852

RESUMO

Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development of new techniques and insights has led to a deeper understanding of the mechanisms underlying these conditions and opened up new avenues for diagnosis and treatment. In this review, we discussed the rise of metabolic diseases, especially in Western countries, the genetical, psychological, and behavioral basis of metabolic diseases, the role of nutrition and physical activity in the development of metabolic diseases, the role of single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, and cell-based therapies in metabolic diseases. Finally, practical applications derived from this information are made.


Assuntos
Microbioma Gastrointestinal , Doenças Metabólicas , Humanos , Doenças Metabólicas/terapia , Doenças Metabólicas/metabolismo , Epigênese Genética
13.
Nutrients ; 15(14)2023 Jul 11.
Artigo em Inglês | MEDLINE | ID: mdl-37513524

RESUMO

This comprehensive narrative review explores the concept of neuro-vulnerability in energy metabolism regulation and its implications for metabolic disorders. The review highlights the complex interactions among the neural, hormonal, and metabolic pathways involved in the regulation of energy metabolism. The key topics discussed include the role of organs, hormones, and neural circuits in maintaining metabolic balance. The review investigates the association between neuro-vulnerability and metabolic disorders, such as obesity, insulin resistance, and eating disorders, considering genetic, epigenetic, and environmental factors that influence neuro-vulnerability and subsequent metabolic dysregulation. Neuroendocrine interactions and the neural regulation of food intake and energy expenditure are examined, with a focus on the impact of neuro-vulnerability on appetite dysregulation and altered energy expenditure. The role of neuroinflammation in metabolic health and neuro-vulnerability is discussed, emphasizing the bidirectional relationship between metabolic dysregulation and neuroinflammatory processes. This review also evaluates the use of neuroimaging techniques in studying neuro-vulnerability and their potential applications in clinical settings. Furthermore, the association between neuro-vulnerability and eating disorders, as well as its contribution to obesity, is examined. Potential therapeutic interventions targeting neuro-vulnerability, including pharmacological treatments and lifestyle modifications, are reviewed. In conclusion, understanding the concept of neuro-vulnerability in energy metabolism regulation is crucial for addressing metabolic disorders. This review provides valuable insights into the underlying neurobiological mechanisms and their implications for metabolic health. Targeting neuro-vulnerability holds promise for developing innovative strategies in the prevention and treatment of metabolic disorders, ultimately improving metabolic health outcomes.


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos , Obesidade , Humanos , Obesidade/metabolismo , Apetite , Hormônios/metabolismo , Metabolismo Energético/fisiologia , Ingestão de Alimentos
14.
Nutrients ; 15(11)2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-37299557

RESUMO

Anorexia nervosa is a psychiatric disorder with an unknown etiology that is characterized by an individual's preoccupation with their weight and body structure while denying the severity of their low body weight. Due to the fact that anorexia nervosa is multifaceted and may indicate the coexistence of genetic, social, hormonal, and psychiatric disorders, a description of non-pharmacological interventions can be used to ameliorate or reduce the symptoms of this condition. Consequently, the purpose of the present narrative review is to describe the profile's context in the anorexic person as well as the support they would require from their family and environment. In addition, it is aimed at examining preventative and non-pharmacological interventions, such as nutritional interventions, physical activity interventions, psychological interventions, psychosocial interventions, and physical therapy interventions. To reach the narrative review aims, a critical review was conducted utilizing both primary sources, such as scientific publications, and secondary sources, such as bibliographic indexes, web pages, and databases. Nutritional interventions include nutritional education and an individualized treatment for each patient, physical activity interventions include allowing patients to perform controlled physical activity, psychological interventions include family therapy and evaluation of the existence of other psychological disorders, psychosocial interventions include management of the relationship between the patient and social media and physical therapy interventions include relaxation massages and exercises to relieve pain. All these non-pharmacological interventions need to be individualized based on each patient's needs.


Assuntos
Anorexia Nervosa , Humanos , Anorexia Nervosa/psicologia , Anorexia , Terapia Familiar
15.
Int. j. morphol ; 41(3): 845-850, jun. 2023. tab
Artigo em Inglês | LILACS | ID: biblio-1514299

RESUMO

SUMMARY: The aim of this cross-sectional study was to compare dietary intake to published recommendations and to analyze the potential relationship between body composition and dietary intake in collegiate athletes. Eighteen healthy male middle- and long- distance runners (age 20.11 ± 2.72 y; height, 174.7 ± 6.1 cm; body mass, 64.0 ± 7.7 kg), were recruited from a Mexican university track and field team at the beginning of the general preparation phase for national competitions. Participants completed three 24-hour dietary recalls, which were used to estimate dietary intake. Body composition was measured by Dual-energy X-ray absorptiometry (DXA). Athletes displayed high body fat values. Protein intake was significantly higher than published recommendations. Iron, zinc, sodium, and vitamin C intake were significantly higher than recommended values, while potassium and calcium intake were below established recommendations. No significant correlations between body composition variables (i.e body fat, lean body mass, bone mineral content) and dietary intake (i.e energy, macronutrients and selected vitamins and minerals) could be found. These findings suggest that coaches and practitioners should pay close attention to dietary intake and body composition of endurance athletes starting general preparation for competition. Future studies on changes of dietary intake and body composition during off-season and competitive phase, which also track physical activity, are warranted.


El objetivo de este estudio transversal fue comparar la ingesta dietética con las recomendaciones publicadas y analizar la relación potencial entre la composición corporal y la ingesta dietética en corredores universitarios. Dieciocho atletas masculinos sanos de media y larga distancia (edad 20,11 ± 2,72 años; altura, 174,7 ± 6,1 cm; masa corporal, 64,0 ± 7,7 kg), fueron reclutados de un equipo de atletismo de una universidad mexicana al comienzo de la fase de preparación general de competiciones nacionales. Los participantes completaron tres recordatorios dietéticos de 24 horas, que se utilizaron para estimar la ingesta dietética. La composición corporal se midió mediante absorciometría de rayos X de energía dual (DXA). Los atletas mostraron altos valores de grasa corporal. La ingesta de proteínas fue significativamente mayor que las recomendaciones publicadas. La ingesta de hierro, zinc, sodio y vitamina C fue significativamente superior a los valores recomendados, mientras que la ingesta de potasio y calcio estuvo por debajo de las recomendaciones establecidas. No se encontraron correlaciones significativas entre las variables de composición corporal (es decir, grasa corporal, masa corporal magra, contenido mineral óseo) y la ingesta dietética (es decir, energía, macronutrientes y vitaminas y minerales seleccionados). Estos hallazgos sugieren que los entrenadores y los practicantes deberían prestar mucha atención a la ingesta dietética y la composición corporal de los atletas de resistencia que comienzan la preparación general para la competencia. Se justifican estudios futuros sobre los cambios en la ingesta dietética y la composición corporal durante la fase fuera de temporada y competitiva, como también un seguimiento de la actividad física.


Assuntos
Humanos , Masculino , Adulto Jovem , Corrida , Composição Corporal , Dieta , Ingestão de Alimentos , Estudantes , Universidades , Absorciometria de Fóton , Tecido Adiposo , Estudos Transversais
16.
Int J Mol Sci ; 24(10)2023 May 16.
Artigo em Inglês | MEDLINE | ID: mdl-37240194

RESUMO

Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of mitochondria from one cell to another, has recently emerged as a potential therapeutic approach for restoring mitochondrial function in diseased cells. In this review, we summarize the current understanding of mitochondrial transfer, including its mechanisms, potential therapeutic applications, and impact on cell death pathways. We also discuss the future directions and challenges in the field of mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment.


Assuntos
Doenças Metabólicas , Neoplasias , Doenças Neurodegenerativas , Humanos , Mitocôndrias/metabolismo , Doenças Metabólicas/metabolismo , Doenças Neurodegenerativas/diagnóstico , Doenças Neurodegenerativas/terapia , Doenças Neurodegenerativas/metabolismo , Estresse Oxidativo , Neoplasias/diagnóstico , Neoplasias/terapia , Neoplasias/metabolismo
17.
Rev Esp Geriatr Gerontol ; 58(2): 96-103, 2023.
Artigo em Espanhol | MEDLINE | ID: mdl-37005188

RESUMO

BACKGROUND AND OBJECTIVE: In this article we sought to characterize the Long Stay Establishments for the Elderly in Chile, besides presenting the services offered in the public and private. MATERIAL AND METHODS: It is a quantitative, cross-sectional descriptive study, with secondary information source. We analyze all establishments in the country registered with the National Service of the Elderly. As of November 2015, a total of 724 establishments were registered and distributed in 169 neighborhoods throughout the country in which 16,985 adults aged 60 and over were institutionalized. RESULTS: Most of the establishments (65.9% [n=246/724]) are private, 47.5% of them (n=344/724) are located in the metropolitan region of Santiago. Of the residents' health, only 26.5% are considered functional brave, 28.3% are physically handicapped and 8.8% are mentally handicapped. Most establishments offer manual activities, physical exercises, memory classes, cultural classes and recreational or touristic tours. Proportionally of the activities offered were mostly private ones. CONCLUSIONS: In Chile, most of the establishments are private, located in the metropolitan region where there is the largest supply deficit of this type of service, with an occupancy rate of 90.7%, with 72.4% women and almost half 47.7% with some physical or psychic dependence.


Assuntos
Estudos Transversais , Idoso , Humanos , Feminino , Pessoa de Meia-Idade , Masculino , Chile
18.
Rev. esp. geriatr. gerontol. (Ed. impr.) ; 58(2): 96-103, mar.-abr. 2023.
Artigo em Espanhol | IBECS | ID: ibc-219618

RESUMO

Antecedentes y objetivo: En este artículo sé buscó caracterizar los establecimientos de larga estancia para adultos mayores (ELEAM) de Chile, además de presentar los servicios ofrecidos en lo público y en lo privado. Material y métodos: Se trata de un estudio cuantitativo, transversal descriptivo, a través de fuente de información secundaria. Analizamos todos los ELEAM del país registrados en el Servicio Nacional del Adulto Mayor (SENAMA). Hasta noviembre de 2015 un total de 724 ELEAM estaban registrados y distribuidos en 169 comunas alrededor del país, en los cuales estaban institucionalizados 16.985 adultos con edad a partir de los 60años. Resultados: La mayoría de los ELEAM (65,9% [n=344/724]) son privados. Entre ellos, el 47,5% (n=246/724) están localizados en la región metropolitana de Santiago. De la salud de los residentes, apenas el 26,5% son considerados autosuficientes funcionales, el 28,3% son deficientes físicos y el 8,8%, deficientes psíquicos. La mayoría de los establecimientos ofrecen actividades manuales, ejercicios físicos, clases de memoria, clases culturales y paseos recreativos o turísticos. Proporcionalmente, la mayoría de las actividades ofrecidas eran privadas. Conclusiones: En Chile la mayor parte de los establecimientos son de carácter privado, ubicados en la región metropolitana, donde se encuentra un mayor déficit de oferta de este servicio, con una tasa de ocupación del 90,7%, siendo el 72,4% mujeres, y casi la mitad (47,7%) con alguna dependencia física o psíquica. (AU)


Background and objective: In this article we sought to characterize the Long Stay Establishments for the Elderly in Chile, besides presenting the services offered in the public and private. Material and methods: It is a quantitative, cross-sectional descriptive study, with secondary information source. We analyze all establishments in the country registered with the National Service of the Elderly. As of November 2015, a total of 724 establishments were registered and distributed in 169 neighborhoods throughout the country in which 16,985 adults aged 60 and over were institutionalized. Results: Most of the establishments (65.9% [n=246/724]) are private, 47.5% of them (n=344/724) are located in the metropolitan region of Santiago. Of the residents’ health, only 26.5% are considered functional brave, 28.3% are physically handicapped and 8.8% are mentally handicapped. Most establishments offer manual activities, physical exercises, memory classes, cultural classes and recreational or touristic tours. Proportionally of the activities offered were mostly private ones. Conclusions: In Chile, most of the establishments are private, located in the metropolitan region where there is the largest supply deficit of this type of service, with an occupancy rate of 90.7%, with 72.4% women and almost half 47.7% with some physical or psychic dependence. (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Tempo de Internação , Casas de Saúde , Política Pública , Estudos Transversais , Epidemiologia Descritiva , Chile , Instituição de Longa Permanência para Idosos , Envelhecimento
19.
Artigo em Inglês | MEDLINE | ID: mdl-36901425

RESUMO

The aim of the present research was to analyze the effect of anxiety levels during the COVID-19 pandemic in the use of social media and compliance with lockdown measures during the confinement. A total of 1723 participants (32.1% males and 77.9% females; 32.6 ± 9.2 years) were interviewed by a Spanish version of the Spielberger State-Trait Anxiety Inventory. From the results obtained, the sample was divided into two 50th percentile groups, a high anxiety group (HAG) and a low anxiety group (LAG). We found how the LAG had lower use of social networks such as Facebook and Twitter during confinement. Also, this group presented a higher rate of leaving home during the confinement and higher values in people with whom they had lived with during confinement than high anxiety group. Regardless of the lack of results in the remaining variables, the present study nuances the high levels of anxiety experienced during COVID-19 confinement. The multifactorial analysis of factors related to the perception of anxiety during COVID-19 confinement may be a useful tool to measure multiple social behaviors when examining mental health factors. Thus, explaining and preventing the psychological consequences of the COVID-19 pandemic. The present knowledge could be used to determine key intervention factors for reducing the perception of fear and anxiety.


Assuntos
COVID-19 , Mídias Sociais , Masculino , Feminino , Humanos , COVID-19/psicologia , SARS-CoV-2 , Pandemias/prevenção & controle , Controle de Doenças Transmissíveis , Ansiedade
20.
Metabolites ; 13(2)2023 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-36837787

RESUMO

Energy deficits are often observed in athletes, especially in female athletes, due to the high expenditure of sport and strict diets. Low energy availability can cause serious health problems and affect sport performance. The aim of this study was to evaluate the effects of different personalized dietary plans on physiological and physical factors related to energy deficit syndrome in female professional handball players. Twenty-one professional female handball players, aged 22 ± 4 years, 172.0 ± 5.4 cm and 68.4 ± 6.7 kg, divided into three groups (FD: free diet; MD: Mediterranean diet; and AD: high antioxidant diet), participated in this 12-week randomized controlled trial. Energy expenditure through indirect calorimetry, energy availability, 7 day dietary intake analysis, blood pressure, cholesterol, menstrual function, body composition by both anthropometry and bioelectrical impedance, and strength performance were assessed. All participants showed low energy availability (<30 kcal/lean mass per day); despite this, all had eumenorrhea. Significant improvements were found after the intervention in all components of body composition (p < 0.05). In the remaining variables, despite slight improvements, none were significant neither over time nor between the different groups. Low energy availability has been observed in all professional female handball players, which may lead to serious consequences. A longer period of intervention is required to assess the differences between diets and improvements in other parameters.

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